Incubator Shaker
Multitron
Incubator Shaker
Multitron
Minimize interruptions and ensure optimal productivity at every step of your bioprocess
The Multitron incubator shaker is an application-oriented shaker, configured specifically for your cell culture or microbial process conditions.
Advantages
Parallel processing in optimal growth conditions, handling screening and production in tandem. Compact design with large internal capacity, a triple stacked system has ample capacity that can be used to cultivate 63 L or 23,000 experiments in parallel in less than a square meter of space.
Maintain a reliable environment for your cells with reproducible results across all trays due to the high-degree of temperature uniformity, and precision during your uninterrupted 24/7 operation.
Designed with reducing lab contamination in mind, the Multitron Incubator Shaker has rounded corners that make interior cleaning easy. The bottom well is accessible for cleaning and the optional UV emission source in the air flow path provides additional safety.
Parallel processing in optimal growth conditions, handling screening and production in tandem. Compact design with large internal capacity, a triple stacked system has ample capacity that can be used to cultivate 63 L or 23,000 experiments in parallel in less than a square meter of space.
Maintain a reliable environment for your cells with reproducible results across all trays due to the high-degree of temperature uniformity, and precision during your uninterrupted 24/7 operation.
Designed with reducing lab contamination in mind, the Multitron Incubator Shaker has rounded corners that make interior cleaning easy. The bottom well is accessible for cleaning and the optional UV emission source in the air flow path provides additional safety.
Experience parallel processing
What if there was a single incubator shaker that could handle both screening and production at the same time with a configuration tailored to your needs, increasing your process development speeds and reducing your time to market?
Worried about lab space?
The Multitron incubator shaker, compared to its competitors, has an ideal working height of 140 cm on the upper unit and ensures easy access to the user. Even with the door opened, the maximum height reaches 180 cm, taking up minimal lab space.
Product specifications
- Shipped pre-configured and stacked. Available configurations: 1 floor standing or benchtop unit, or a two- or three-stacked unit, and optional top cooling units are available.
- Ideal working height at 29 cm for a single-stack unit and 140 cm for a triple-stacked system, allows users to easily access all cabinets
- Small overall footprint: 1070 mm x 880 mm with minimal ventilation gap clearance needed, 8 cm on each side.
- Choose from these orbital throws: 3 mm for high-throughput screening (with 96 deep well plates), 25 mm, 50 mm, or an adjustable throw (15.5 mm, 19 mm, 25 mm, or 50 mm)
- LED Lighting: Uniform, energy-efficient LEDs (240 μmol m⁻²s⁻¹) enable phototrophic growth with day-night cycle simulation via eve® software.
Product downloads
Related publications
All publicationsResearchers from the University of Delaware, Departments of Chemical and Biomolecular Engineering and Electrical and Computer Engineering have made strides in enhancing the resilience of Chinese hamster ovary (CHO) cells used in biopharmaceutical production. By employing the INFORS HT Multitron incubator shaker, they exposed CHO cells to stress conditions commonly encountered during manufacturing, such as elevated levels of ammonia, lactate, and osmolality. Through comprehensive transcriptomic analysis, the team identified 199 genes exhibiting bistable expression, with seven emerging as prime candidates for engineering stress-resistant cell lines. This research holds promise for optimizing cell health and boosting productivity in large-scale bioreactor operations.
Researchers from the University of Delaware's Department of Chemical and Biomolecular Engineering have developed a site-specific integration (SSI) system to streamline CHO cell line development for monoclonal antibody (mAb) production. Using the INFORS HT Multitron incubator shaker, they cultivated cells under optimized conditions to evaluate a recombinase-mediated cassette exchange (RMCE) system that enables high-throughput transgene selection without cell sorting. Their approach resulted in a 7- to 11-fold increase in mAb productivity, offering a faster and more reliable method for biopharmaceutical manufacturing.
Researchers from Albert Einstein College of Medicine, Adimab LLC, and the U.S. Army Medical Research Institute of Infectious Diseases explored how combining neutralizing antibodies targeting different parts of the SARS-CoV-2 spike protein can help prevent escape mutants. Using the INFORS HT Multitron incubator shaker, they cultivated cells under controlled conditions to test antibody effectiveness. Their approach could strengthen antibody-based COVID-19 treatments by improving effectiveness and reducing resistance.
Researchers from the University of Delaware, Departments of Chemical and Biomolecular Engineering and Electrical and Computer Engineering have made strides in enhancing the resilience of Chinese hamster ovary (CHO) cells used in biopharmaceutical production. By employing the INFORS HT Multitron incubator shaker, they exposed CHO cells to stress conditions commonly encountered during manufacturing, such as elevated levels of ammonia, lactate, and osmolality. Through comprehensive transcriptomic analysis, the team identified 199 genes exhibiting bistable expression, with seven emerging as prime candidates for engineering stress-resistant cell lines. This research holds promise for optimizing cell health and boosting productivity in large-scale bioreactor operations.
Researchers from the University of Delaware's Department of Chemical and Biomolecular Engineering have developed a site-specific integration (SSI) system to streamline CHO cell line development for monoclonal antibody (mAb) production. Using the INFORS HT Multitron incubator shaker, they cultivated cells under optimized conditions to evaluate a recombinase-mediated cassette exchange (RMCE) system that enables high-throughput transgene selection without cell sorting. Their approach resulted in a 7- to 11-fold increase in mAb productivity, offering a faster and more reliable method for biopharmaceutical manufacturing.
Researchers from Albert Einstein College of Medicine, Adimab LLC, and the U.S. Army Medical Research Institute of Infectious Diseases explored how combining neutralizing antibodies targeting different parts of the SARS-CoV-2 spike protein can help prevent escape mutants. Using the INFORS HT Multitron incubator shaker, they cultivated cells under controlled conditions to test antibody effectiveness. Their approach could strengthen antibody-based COVID-19 treatments by improving effectiveness and reducing resistance.
Perfecting HEK293 Cells for Gene Therapy - The Role of Incubator Flexibility
Unlock the secrets to optimizing HEK293 cell cultures for gene therapy applications in our latest webinar. Discover how the flexibility of incubators plays a vital role in maximizing viral vector production. Watch now and read the application note to explore:
- The importance of HEK293 cells in gene therapy.
- Customizable incubator parameters that optimize growth conditions.
- The influence of humidity, temperature, and orbital diameter on production efficiency.
Water for Incubators
After years of feedback and study, INFORS HT has developed Water for Incubators. It is double distilled, 0.1µm filter sterilized, has a pH of 7-9 with a conductivity of 1-20 µS/cm, and is terminal sterilized. The water formulation removes certain divalent ions and raises the pH to fight off waterborne bacteria and fungi to provide a sterile culture environment.
Customer voices
Rui de Paula Vieira de CastroAssociate Scientist, Jefferson Institute of Bioprocessing (JIB)
Nicole Lapuyade-BakerSenior Research Associate at CytomX Therapeutics
Matthew HigginsDepartment of Biochemistry at the University of Oxford, UK
Delivering excellence in antibody discovery
INFORS HT partners with FairJourney Biologics, an innovative contract research organization (CRO) to deliver excellence in antibody discovery and production.
Related articles
See allIn bioprocessing, selecting the right shaker parameters is essential for optimizing the growth and productivity of various organisms, including bacteria, yeast, and mammalian cells. By fine-tuning these parameters, scientists can create ideal environments for cultivation, maximizing process efficiency and reproducibility. In this installment of our Back to Basics blog series, we focus on how INFORS HT incubator shakers enable better control and flexibility to meet diverse cultivation needs.
Gene therapy is a promising approach for treating various genetic disorders and diseases. A critical component of gene therapy is the production of viral vectors, which serve as delivery vehicles for therapeutic genes. Human Embryonic Kidney 293 (HEK293) cells have become a widely used platform for viral vector production due to their efficiency in transfection and ability to support viral replication. However, optimizing HEK293 cell cultures for large-scale production of viral vectors remains a challenge in making gene therapies more accessible and cost-effective.
Maintaining a sterile environment is essential in bioprocess laboratories, particularly when working with sensitive cell cultures or microbial samples. Contamination not only jeopardizes experimental results, but it can also lead to costly downtime and wasted resources. In this first installment of our Back to Basics blog series, we focus on the role of UV decontamination in incubator shakers and how it serves as an effective risk mitigation strategy.
In bioprocessing, selecting the right shaker parameters is essential for optimizing the growth and productivity of various organisms, including bacteria, yeast, and mammalian cells. By fine-tuning these parameters, scientists can create ideal environments for cultivation, maximizing process efficiency and reproducibility. In this installment of our Back to Basics blog series, we focus on how INFORS HT incubator shakers enable better control and flexibility to meet diverse cultivation needs.
Gene therapy is a promising approach for treating various genetic disorders and diseases. A critical component of gene therapy is the production of viral vectors, which serve as delivery vehicles for therapeutic genes. Human Embryonic Kidney 293 (HEK293) cells have become a widely used platform for viral vector production due to their efficiency in transfection and ability to support viral replication. However, optimizing HEK293 cell cultures for large-scale production of viral vectors remains a challenge in making gene therapies more accessible and cost-effective.
Maintaining a sterile environment is essential in bioprocess laboratories, particularly when working with sensitive cell cultures or microbial samples. Contamination not only jeopardizes experimental results, but it can also lead to costly downtime and wasted resources. In this first installment of our Back to Basics blog series, we focus on the role of UV decontamination in incubator shakers and how it serves as an effective risk mitigation strategy.
Ideal offerings to further optimize your bioprocess workflow
Our global network of experienced technicians is here to help ensure your incubator shakers operate 24/7.
Enhance your laboratory shaker with a wide range of trays, holders, and adhesive mats.
Our laboratory shakers stand out for their intelligent, ergonomic design and utilization of the latest technologies.
Our global network of experienced technicians is here to help ensure your incubator shakers operate 24/7.
Enhance your laboratory shaker with a wide range of trays, holders, and adhesive mats.
Our laboratory shakers stand out for their intelligent, ergonomic design and utilization of the latest technologies.