Published: 17 févr. 2025(Updated: 17 févr. 2025)
•30 min
•30 min read
•Shrutee Jakhanwal, Brady F Cress, Pascal Maguin, Marco J Lobba, Luciano A Marraffini, Jennifer A DoudnaA CRISPR-Cas9–integrase complex generates precise DNA fragments for genome integration
Cell culture
Scientists from the University of California, Berkeley, and The Rockefeller University have developed an innovative CRISPR-Cas9-integrase complex that enables precise DNA fragment integration, marking a significant leap forward in genome editing technology. The team employed the INFORS HT Multitron incubator shaker to maintain optimal cultivation conditions, ensuring the reliability of their experimental results. This approach is poised to enhance the precision and efficiency of genetic modifications, opening new avenues in biotechnology and therapeutic development.