In this study, researchers have optimized the purification of IL-2 no-alpha mutein using copper-catalyzed air oxidation. This process, using the INFORS HT Techfors pilot bioreactor, improves the homogeneity and biological activity of the IL-2 agonist, which shows promise in Phase I/II trials for cancer treatment.
Publications
Product
In this study, researchers have optimized the purification of IL-2 no-alpha mutein using copper-catalyzed air oxidation. This process, using the INFORS HT Techfors pilot bioreactor, improves the homogeneity and biological activity of the IL-2 agonist, which shows promise in Phase I/II trials for cancer treatment.
This study, on ASM Journals, discusses promising methods to selectively identify phenotypes in B. subtilis with improved tolerance toward oxidative and disulfide-associated stress. The Multitron incubator shaker was used to quickly screen large libraries of transposon mutants for those bacteria that show enhanced tolerance towards oxidative stress.
This scientific research paper on ScienceDirect highlights the Multitron incubator shaker as a tool for enhancing productivity of simultaneous screening of genetic designs and chassis during the build step of metabolic engineering.
This study, published on ScienceDirect, aimed to revolutionize bioproduction by developing a cost-effective, robust, and scalable platform using a novel approach with C. glutamicum and UF-SSL. This research eliminates costly media additives and energy-intensive detoxification steps, paving the way for more efficient and sustainable industrial ethanol production.
The goal of this research. conduced at Karolinska Institutet in Stockholm, Sweden, was to improve the productivity of human Bri2 BRICHOS domain production. The human Bri2 BRICHOS domain inhibits amyloid formation and toxicity and could be used as a therapeutic agent against amyloid diseases, such as alzheimers disease.
This research that was conducted at the Technical University of Munich, where scientists utilized an INFORS HT Techfors pilot bioreactor to evaluate and refine the expression of L-cysteine (amino acid widely used in pharmaceutical, food, feed, and cosmetic industries) synthases, achieving a productivity improvement of ~70%.
This research was done by Nikhil Seshagiri Rao, Ph.D. and a team of scientists at Lund University in Sweden, published in the journal, Frontiers in Microbiology, where they utilized the INFORS HT Minifors bioreactor system with eve® bioprocess platform software to evaluate the effects of oxygen during cultivation on freeze-drying stress tolerance.
Researchers at University of Applied Sciences and Arts Northwestern Switzerland FHNW worked to develop a rapid test that measures patient immune protection from SARS-CoV-2, resulting from prior infection or vaccination. Their work utilized INFORS HT's Techfors-S pilot bioreactor.
Researchers at Technische Universität Wien sought to develop simplified and improved methods for monitoring and predicting cell viability in bioprocesses with complex expression systems, such as filamentous fungi. Their work utilized the INFORS HT Techfors-S pilot bioreactor.
A study conducted by LanzaTech, published in Biotechnology for Biofuels, explores how Clostridium autoethanogenum (an acetogenic bacterium) adapts to various hydrogen ratios in its feedstock. The focus of this study is to enhance carbon capture efficiency with a spotlight on CO₂ conversion. This research unveils the metabolic adaptations of C. autoethanogenum and paves the way for innovative bioengineering strategies to maximize CO₂ conversion in industrial applications.
This study, on ASM Journals, discusses promising methods to selectively identify phenotypes in B. subtilis with improved tolerance toward oxidative and disulfide-associated stress. The Multitron incubator shaker was used to quickly screen large libraries of transposon mutants for those bacteria that show enhanced tolerance towards oxidative stress.
This scientific research paper on ScienceDirect highlights the Multitron incubator shaker as a tool for enhancing productivity of simultaneous screening of genetic designs and chassis during the build step of metabolic engineering.
This study, published on ScienceDirect, aimed to revolutionize bioproduction by developing a cost-effective, robust, and scalable platform using a novel approach with C. glutamicum and UF-SSL. This research eliminates costly media additives and energy-intensive detoxification steps, paving the way for more efficient and sustainable industrial ethanol production.
The goal of this research. conduced at Karolinska Institutet in Stockholm, Sweden, was to improve the productivity of human Bri2 BRICHOS domain production. The human Bri2 BRICHOS domain inhibits amyloid formation and toxicity and could be used as a therapeutic agent against amyloid diseases, such as alzheimers disease.
This research that was conducted at the Technical University of Munich, where scientists utilized an INFORS HT Techfors pilot bioreactor to evaluate and refine the expression of L-cysteine (amino acid widely used in pharmaceutical, food, feed, and cosmetic industries) synthases, achieving a productivity improvement of ~70%.
This research was done by Nikhil Seshagiri Rao, Ph.D. and a team of scientists at Lund University in Sweden, published in the journal, Frontiers in Microbiology, where they utilized the INFORS HT Minifors bioreactor system with eve® bioprocess platform software to evaluate the effects of oxygen during cultivation on freeze-drying stress tolerance.
Researchers at University of Applied Sciences and Arts Northwestern Switzerland FHNW worked to develop a rapid test that measures patient immune protection from SARS-CoV-2, resulting from prior infection or vaccination. Their work utilized INFORS HT's Techfors-S pilot bioreactor.
Researchers at Technische Universität Wien sought to develop simplified and improved methods for monitoring and predicting cell viability in bioprocesses with complex expression systems, such as filamentous fungi. Their work utilized the INFORS HT Techfors-S pilot bioreactor.
A study conducted by LanzaTech, published in Biotechnology for Biofuels, explores how Clostridium autoethanogenum (an acetogenic bacterium) adapts to various hydrogen ratios in its feedstock. The focus of this study is to enhance carbon capture efficiency with a spotlight on CO₂ conversion. This research unveils the metabolic adaptations of C. autoethanogenum and paves the way for innovative bioengineering strategies to maximize CO₂ conversion in industrial applications.