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18 déc. 2024
34 min read
Recombinant laccase biosynthesis for efficient polydopamine coating

In a study from the University of Aveiro, researchers leveraged the INFORS HT Minifors bench-top bioreactor to optimize recombinant laccase production in Komagataella phaffii. By fine-tuning cultivation conditions, they scaled laccase production and demonstrated its stability and effectiveness as a biocatalyst. Notably, this laccase was used to assist dopamine polymerization, achieving an innovative polydopamine coating on filter paper, an exciting advance in enzyme applications for material science.

18 déc. 202434 min read
Recombinant laccase biosynthesis for efficient polydopamine coating

In a study from the University of Aveiro, researchers leveraged the INFORS HT Minifors bench-top bioreactor to optimize recombinant laccase production in Komagataella phaffii. By fine-tuning cultivation conditions, they scaled laccase production and demonstrated its stability and effectiveness as a biocatalyst. Notably, this laccase was used to assist dopamine polymerization, achieving an innovative polydopamine coating on filter paper, an exciting advance in enzyme applications for material science.

18 déc. 202428 min read
Optimum blue light exposure: a means to increase cell-specific productivity in Chinese hamster ovary cells

Researchers at the University of Stuttgart discovered that blue LED light exposure can boost CHO cell productivity by 57%. Using the INFORS HT Minitron incubator shaker, they demonstrated how precise light optimization offers a simple, non-invasive approach to enhancing biopharmaceutical production. This breakthrough could enhance efficiency in bioreactors.

02 déc. 202440 min read
Chemical mixture effects on the simplified human intestinal microbiota: Assessing xenobiotics at environmentally realistic concentrations

Researchers at Helmholtz-Centre for Environmental Research UFZ GmbH, Leipzig, explored the effects of xenobiotics on gut microbiota using the Multifors bench-top bioreactor. Their findings highlight the impact of environmental contaminants like PFAS and BPX on microbial communities and metabolic pathways, emphasizing the need to consider these interactions for public health.

25 nov. 202447 min read
Investigating biological mechanisms of colour changes in sustainable food systems: The role of Starmerella bacillaris in white wine colouration

Researchers at the Norwegian University of Life Sciences explored how yeast strains can naturally enhance color in white wine fermentation. Using the INFORS HT Multifors bioreactor and eve software, they examined Starmerella bacillaris strains that influence wine color, polyphenol content, and antioxidant properties. The findings suggest that S. bacillaris offers an eco-friendly alternative to artificial additives in winemaking, highlighting its potential to improve food quality naturally. This study paves the way for sustainable practices and innovative applications in food production and fermentation.

25 nov. 202444 min read
A new β-galactosidase from Paenibacillus wynnii with potential for industrial applications

Researchers at the University of Hohenheim, Stuttgart, used the INFORS HT Minifors bioreactor to cultivate a promising new beta-galactosidase enzyme from Paenibacillus wynnii. Known as BgaPw, this enzyme excels in lactose hydrolysis with impressive activity and resistance to product inhibition, paving the way for industrial applications in lactose conversion.

25 nov. 202452 min read
Metabolic bottlenecks of Pseudomonas taiwanensis VLB120 during growth on d-xylose via the Weimberg pathway

Researchers at TU Dortmund University have uncovered metabolic bottlenecks in Pseudomonas taiwanensis during growth on d-xylose, using the INFORS HT Multitron Standard incubator shaker. Their findings offer new insights into optimizing the Weimberg pathway for bioprocesses on renewable feedstocks, advancing strain development and bioproduction.

25 nov. 202436 min read
Characterization of bacterial cellulose produced by the KomEt strain isolated from a kombucha SCOBY

Researchers at Université de Sherbrooke have successfully characterized bacterial cellulose (BC) produced from a novel strain isolated from a kombucha SCOBY. Using the Minitron incubator shaker and an INFORS HT bioreactor, they evaluated the mechanical, thermal, and chemical properties of BC, revealing its potential for applications in biomedical, textile, and cosmetic industries.

25 nov. 202449 min read
Achieving high productivity of 2-pyrone-4,6-dicarboxylic acid from aqueous aromatic streams with novosphingobium aromaticivorans

Researchers from the University of Wisconsin-Madison utilized an optimized Multifors bench-top bioreactor system to significantly enhance the production of 2-pyrone-4,6-dicarboxylic acid (PDC) from aqueous aromatic streams using Novosphingobium aromaticivorans. Their findings demonstrate how membrane separation and pH control improvements boost PDC yields, advancing the production of biochemicals from lignocellulosic biomass for polymer-based materials.

25 nov. 202438 min read
Cell-free gene expression in bioprinted fluidic networks

Researchers from the School of Natural Sciences at TU Munich utilized the Minifors bench-top bioreactor to support their innovative experiment on cell-free gene expression in bioprinted fluidic networks. This study highlights how integrating cell-free protein synthesis into vascularized hydrogels enables dynamic molecular control, providing valuable insights for creating synthetic biomaterials that mimic biological functions.

25 nov. 202460 min read
Crimean-Congo hemorrhagic fever survivors elicit protective non-neutralizing antibodies that target 11 overlapping regions on glycoprotein GP38

Researchers at Adimab, LLC isolated 188 monoclonal antibodies against Crimean-Congo hemorrhagic fever virus (CCHFV) GP38 from human survivors. While non-neutralizing, these antibodies target 11 overlapping sites and demonstrate protective efficacy in rodent models. This study provides valuable insights into CCHFV viral glycoprotein and could aid the development of antibody therapeutics for this lethal virus.

18 déc. 202428 min read
Optimum blue light exposure: a means to increase cell-specific productivity in Chinese hamster ovary cells

Researchers at the University of Stuttgart discovered that blue LED light exposure can boost CHO cell productivity by 57%. Using the INFORS HT Minitron incubator shaker, they demonstrated how precise light optimization offers a simple, non-invasive approach to enhancing biopharmaceutical production. This breakthrough could enhance efficiency in bioreactors.

02 déc. 202440 min read
Chemical mixture effects on the simplified human intestinal microbiota: Assessing xenobiotics at environmentally realistic concentrations

Researchers at Helmholtz-Centre for Environmental Research UFZ GmbH, Leipzig, explored the effects of xenobiotics on gut microbiota using the Multifors bench-top bioreactor. Their findings highlight the impact of environmental contaminants like PFAS and BPX on microbial communities and metabolic pathways, emphasizing the need to consider these interactions for public health.

25 nov. 202447 min read
Investigating biological mechanisms of colour changes in sustainable food systems: The role of Starmerella bacillaris in white wine colouration

Researchers at the Norwegian University of Life Sciences explored how yeast strains can naturally enhance color in white wine fermentation. Using the INFORS HT Multifors bioreactor and eve software, they examined Starmerella bacillaris strains that influence wine color, polyphenol content, and antioxidant properties. The findings suggest that S. bacillaris offers an eco-friendly alternative to artificial additives in winemaking, highlighting its potential to improve food quality naturally. This study paves the way for sustainable practices and innovative applications in food production and fermentation.

25 nov. 202444 min read
A new β-galactosidase from Paenibacillus wynnii with potential for industrial applications

Researchers at the University of Hohenheim, Stuttgart, used the INFORS HT Minifors bioreactor to cultivate a promising new beta-galactosidase enzyme from Paenibacillus wynnii. Known as BgaPw, this enzyme excels in lactose hydrolysis with impressive activity and resistance to product inhibition, paving the way for industrial applications in lactose conversion.

25 nov. 202452 min read
Metabolic bottlenecks of Pseudomonas taiwanensis VLB120 during growth on d-xylose via the Weimberg pathway

Researchers at TU Dortmund University have uncovered metabolic bottlenecks in Pseudomonas taiwanensis during growth on d-xylose, using the INFORS HT Multitron Standard incubator shaker. Their findings offer new insights into optimizing the Weimberg pathway for bioprocesses on renewable feedstocks, advancing strain development and bioproduction.

25 nov. 202436 min read
Characterization of bacterial cellulose produced by the KomEt strain isolated from a kombucha SCOBY

Researchers at Université de Sherbrooke have successfully characterized bacterial cellulose (BC) produced from a novel strain isolated from a kombucha SCOBY. Using the Minitron incubator shaker and an INFORS HT bioreactor, they evaluated the mechanical, thermal, and chemical properties of BC, revealing its potential for applications in biomedical, textile, and cosmetic industries.

25 nov. 202449 min read
Achieving high productivity of 2-pyrone-4,6-dicarboxylic acid from aqueous aromatic streams with novosphingobium aromaticivorans

Researchers from the University of Wisconsin-Madison utilized an optimized Multifors bench-top bioreactor system to significantly enhance the production of 2-pyrone-4,6-dicarboxylic acid (PDC) from aqueous aromatic streams using Novosphingobium aromaticivorans. Their findings demonstrate how membrane separation and pH control improvements boost PDC yields, advancing the production of biochemicals from lignocellulosic biomass for polymer-based materials.

25 nov. 202438 min read
Cell-free gene expression in bioprinted fluidic networks

Researchers from the School of Natural Sciences at TU Munich utilized the Minifors bench-top bioreactor to support their innovative experiment on cell-free gene expression in bioprinted fluidic networks. This study highlights how integrating cell-free protein synthesis into vascularized hydrogels enables dynamic molecular control, providing valuable insights for creating synthetic biomaterials that mimic biological functions.

25 nov. 202460 min read
Crimean-Congo hemorrhagic fever survivors elicit protective non-neutralizing antibodies that target 11 overlapping regions on glycoprotein GP38

Researchers at Adimab, LLC isolated 188 monoclonal antibodies against Crimean-Congo hemorrhagic fever virus (CCHFV) GP38 from human survivors. While non-neutralizing, these antibodies target 11 overlapping sites and demonstrate protective efficacy in rodent models. This study provides valuable insights into CCHFV viral glycoprotein and could aid the development of antibody therapeutics for this lethal virus.

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