Publications

In a study from the University of Aveiro, researchers leveraged the INFORS HT Minifors bench-top bioreactor to optimize recombinant laccase production in Komagataella phaffii. By fine-tuning cultivation conditions, they scaled laccase production and demonstrated its stability and effectiveness as a biocatalyst. Notably, this laccase was used to assist dopamine polymerization, achieving an innovative polydopamine coating on filter paper, an exciting advance in enzyme applications for material science.

Researchers at the University of Stuttgart discovered that blue LED light exposure can boost CHO cell productivity by 57%. Using the INFORS HT Minitron incubator shaker, they demonstrated how precise light optimization offers a simple, non-invasive approach to enhancing biopharmaceutical production. This breakthrough could enhance efficiency in bioreactors.

Researchers at Helmholtz-Centre for Environmental Research UFZ GmbH, Leipzig, explored the effects of xenobiotics on gut microbiota using the Multifors bench-top bioreactor. Their findings highlight the impact of environmental contaminants like PFAS and BPX on microbial communities and metabolic pathways, emphasizing the need to consider these interactions for public health.

Researchers at TU Dortmund University have uncovered metabolic bottlenecks in Pseudomonas taiwanensis during growth on d-xylose, using the INFORS HT Multitron Standard incubator shaker. Their findings offer new insights into optimizing the Weimberg pathway for bioprocesses on renewable feedstocks, advancing strain development and bioproduction.

Researchers at Université de Sherbrooke have successfully characterized bacterial cellulose (BC) produced from a novel strain isolated from a kombucha SCOBY. Using the Minitron incubator shaker and an INFORS HT bioreactor, they evaluated the mechanical, thermal, and chemical properties of BC, revealing its potential for applications in biomedical, textile, and cosmetic industries.

Researchers from the University of Wisconsin-Madison utilized an optimized Multifors bench-top bioreactor system to significantly enhance the production of 2-pyrone-4,6-dicarboxylic acid (PDC) from aqueous aromatic streams using Novosphingobium aromaticivorans. Their findings demonstrate how membrane separation and pH control improvements boost PDC yields, advancing the production of biochemicals from lignocellulosic biomass for polymer-based materials.

Researchers from the School of Natural Sciences at TU Munich utilized the Minifors bench-top bioreactor to support their innovative experiment on cell-free gene expression in bioprinted fluidic networks. This study highlights how integrating cell-free protein synthesis into vascularized hydrogels enables dynamic molecular control, providing valuable insights for creating synthetic biomaterials that mimic biological functions.

Researchers from the Institute of Bioprocess Engineering and Pharmaceutical Technology at the University of Applied Sciences Mittelhessen have made strides in chemoorganotrophic electrofermentation using Cupriavidus necator. By experimenting with different redox mediators, they identified ferricyanide as a key player in enhancing anodic respiration. With the INFORS HT Multitron providing precise environmental control, the team achieved remarkable current densities, offering a promising solution to the challenges of oxygen-driven fermentation systems.

Researchers from the Department of Parasitology-Mycology at Institut Pasteur de Côte d'Ivoire are exploring new solutions for diagnosing human cysticercosis in remote areas. Their study tested a set of recombinant antigens for use in ELISA assays as a low-cost alternative to neuroimaging. While some challenges remain in optimizing sensitivity, the results show great promise, particularly in regions with limited medical resources. These antigens could provide a crucial screening tool for detecting neurocysticercosis, especially in patients with epilepsy, helping those in remote areas access better diagnosis and care.

Researchers at Adimab, LLC isolated 188 monoclonal antibodies against Crimean-Congo hemorrhagic fever virus (CCHFV) GP38 from human survivors. While non-neutralizing, these antibodies target 11 overlapping sites and demonstrate protective efficacy in rodent models. This study provides valuable insights into CCHFV viral glycoprotein and could aid the development of antibody therapeutics for this lethal virus.