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For scientists just starting in biomanufacturing, the journey from clone screening to GMP manufacturing can feel complex. But with the right tools and knowledge, it is easy to navigate this process efficiently. In this guide, we will break down a step-by-step approach to develop stable, high-yielding cell lines, leveraging tools like incubator shakers and automation software. By the end, you will see how a streamlined workflow simplifies scaling up for preclinical and early clinical production. Plus, we included key data visualizations from our latest scientific poster to highlight critical insights. Download the full document for more details at the conclusion of this blog.

A legacy of customer-centered excellence: For six decades, INFORS HT has built a legacy rooted in customer commitment, innovation, and lasting partnerships. To celebrate this milestone, we are sharing 60 Stories for 60 Years: a collection of inspiring stories from around the world that highlight the people and moments that define INFORS HT. Explore stories that showcase our people and culture, nemorable moments, growth and innovation, and customer successes, each reflecting our dedication to putting customers first. Join us in celebrating the relationships and breakthroughs that have shaped our journey.

In bioprocessing, selecting the right shaker parameters is essential for optimizing the growth and productivity of various organisms, including bacteria, yeast, and mammalian cells. By fine-tuning these parameters, scientists can create ideal environments for cultivation, maximizing process efficiency and reproducibility. In this installment of our Back to Basics blog series, we focus on how INFORS HT incubator shakers enable better control and flexibility to meet diverse cultivation needs.

Gene therapy is a promising approach for treating various genetic disorders and diseases. A critical component of gene therapy is the production of viral vectors, which serve as delivery vehicles for therapeutic genes. Human Embryonic Kidney 293 (HEK293) cells have become a widely used platform for viral vector production due to their efficiency in transfection and ability to support viral replication. However, optimizing HEK293 cell cultures for large-scale production of viral vectors remains a challenge in making gene therapies more accessible and cost-effective.

Maintaining a sterile environment is essential in bioprocess laboratories, particularly when working with sensitive cell cultures or microbial samples. Contamination not only jeopardizes experimental results, but it can also lead to costly downtime and wasted resources. In this first installment of our Back to Basics blog series, we focus on the role of UV decontamination in incubator shakers and how it serves as an effective risk mitigation strategy.

Selecting the correct orbital throw for your incubator shaker is critical for achieving optimal results in cell culture, bacterial growth, and other bioprocessing applications. In this installment of the Back to Basics series, we will explore what orbital throw is, why it matters, and how to make the best choice for your experiments.

At INFORS HT, our mission is to provide superior products and services that improve bioprocess workflows and enable our customers to focus on their core mission. We believe in the power of partnerships that drive innovation, foster growth and deliver exceptional results. Hence we are thrilled to share the success story of FairJourney Biologics, an innovative Contract Research Organization specialized in Antibody Discovery and Production.

Monoclonal antibodies have been used for testing kits and medical therapies across a wide range of applications. The most recent is to provide a potential treatment for patients suffering from COVID-19 infection. The production of monoclonal antibodies is well understood, scalable and standardized to the extent that it makes a good generic example of a modern bioprocess. This aspect will be the focus of this short overview.

As demand for sustainable food sources surges, Daisy Lab is revolutionizing dairy production with precision fermentation technology. By using INFORS HT bioreactors, this New Zealand-based startup is producing animal-free milk proteins like whey and casein. Discover how the innovative process at Daisy Labs, now set to scale with EPA approval, is paving the way for a more sustainable future in dairy.

Stefan Sperling is an industrial designer at the Meyer-Hayoz Design Engineering Group in Switzerland. He is part of the specialist team who was responsible for designing the award-winning INFORS HT Minifors 2 as well as the Multitron and Minitron. In this interview, Mr. Sperling shares his view on what constitutes good product design.