Bioreactors and fermenters for advanced bioprocessing
Bioreactors and fermenters for advanced bioprocessing
Find the right bioreactor for your process
Selecting the right bioreactor or fermentor can be complex, especially when your process needs are evolving. At INFORS HT, we help scientists solve these challenges with bioreactors and fermentors designed for high-performance workflows, including batch culture, fed-batch fermentation, and perfusion. Our systems support a wide variety of applications, offering flexibility and precision from early R&D to pilot-scale and GMP-compliant production. Built on consistent design and shared control platforms, they reduce the need for revalidation and simplify the transition between volumes and applications.
Top advantages of INFORS HT bioreactors and fermentors
Scalable design from lab to pilot
Use similar components, vessel geometries, and control systems across benchtop and pilot scales. This consistency simplifies validation, operator training, and technology transfer.
Expert support from start to scale
From design and installation to maintenance and upgrades, our team works closely with you to adapt your system to evolving process requirements.
Seamless data integration with eve® software
Our bioreactors connect to the eve® platform for full visibility across parameters, automated control, and reliable data tracking during batch, fed-batch, or continuous processes.
Scalable design from lab to pilot
Use similar components, vessel geometries, and control systems across benchtop and pilot scales. This consistency simplifies validation, operator training, and technology transfer.
Expert support from start to scale
From design and installation to maintenance and upgrades, our team works closely with you to adapt your system to evolving process requirements.
Seamless data integration with eve® software
Our bioreactors connect to the eve® platform for full visibility across parameters, automated control, and reliable data tracking during batch, fed-batch, or continuous processes.
Benchtop bioreactors for cell culture and microbial fermentation
Early-stage research and bioprocess development often begin in small volumes. INFORS HT laboratory bioreactors are designed to provide precise control, consistent mixing, and automation-ready functionality for batch and fed-batch processes across a range of microbial and cell culture applications.
Pilot-scale bioreactors for process scale-up
Scaling up bioprocesses introduces new challenges, especially when lab-scale systems lack the control needed at production volumes. INFORS HT pilot bioreactors are built with modular components, real-time monitoring, and advanced automation to ensure what works in the lab can be reproduced at scale.
Browse all INFORS HT bioreactors
A guide for biotech beginners
Download this eBook for basic concepts, recipes, and strategies for bioprocesses involving cell culture and microorganisms.
Our bioreactors are trusted by scientists worldwide
Julia ReisserCo-founder, Uluu
Dr. Tobias ThieleScience Manager, Novonesis, Berlin
Eva Bric-FurlogAutomation Specialist and Scientific Researcher at Sanofi, U.S.
Dr. Maria Ester LuccaMicrobial Biotechnology, Proimi, Argentina
Scientific publications from our customers
See allAt the University of Boras in Sweden, researchers have scaled up second-generation bioethanol production from beech wood chips using an acetone-based organosolv fractionation process. With the help of the INFORS HT Multifors bench-top bioreactor, they confirmed high fermentation efficiency at the 10-L scale, reaching ethanol yields of up to 95% from glucose-rich C6 streams. This study illustrates how optimized biomass pre-treatment and fermentation workflows can drive more efficient and scalable biofuel production.
At Lund University, Division of Food and Pharma, researchers studied the role of annealing in the freeze-drying of probiotic bacteria. Using the INFORS HT Multifors bioreactor and eve software, they controlled the fermentation of Limosilactobacillus reuteri to produce consistent cell cultures for downstream drying. Their results show that increased annealing time leads to thicker encapsulating structures and enhanced storage stability, providing a clearer path to developing more robust probiotic products.
Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg developed and tested methods to improve the stability and recyclability of a PET-degrading enzyme for plastic recycling. Using the INFORS HT Labfors bioreactor, the team compared several immobilization strategies and found that pH-responsive polymers delivered the best results, retaining about 80% of enzyme activity and enabling up to five PET degradation cycles. In batch reactions, the process achieved more than 97% terephthalic acid yield in less than 14 hours for the first three cycles and about 78% yield in the fifth cycle. These findings support more efficient and scalable processes for enzymatic PET recycling.
At the University of Boras in Sweden, researchers have scaled up second-generation bioethanol production from beech wood chips using an acetone-based organosolv fractionation process. With the help of the INFORS HT Multifors bench-top bioreactor, they confirmed high fermentation efficiency at the 10-L scale, reaching ethanol yields of up to 95% from glucose-rich C6 streams. This study illustrates how optimized biomass pre-treatment and fermentation workflows can drive more efficient and scalable biofuel production.
At Lund University, Division of Food and Pharma, researchers studied the role of annealing in the freeze-drying of probiotic bacteria. Using the INFORS HT Multifors bioreactor and eve software, they controlled the fermentation of Limosilactobacillus reuteri to produce consistent cell cultures for downstream drying. Their results show that increased annealing time leads to thicker encapsulating structures and enhanced storage stability, providing a clearer path to developing more robust probiotic products.
Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg developed and tested methods to improve the stability and recyclability of a PET-degrading enzyme for plastic recycling. Using the INFORS HT Labfors bioreactor, the team compared several immobilization strategies and found that pH-responsive polymers delivered the best results, retaining about 80% of enzyme activity and enabling up to five PET degradation cycles. In batch reactions, the process achieved more than 97% terephthalic acid yield in less than 14 hours for the first three cycles and about 78% yield in the fifth cycle. These findings support more efficient and scalable processes for enzymatic PET recycling.
Batch, fed-batch, or continuous?
Explore how batch, fed-batch, and continuous bioprocesses differ in setup, control, and scalability. This article helps you choose the right strategy for your application and system.
Related articles
See allFeeding strategy is one of the most influential variables in any bioprocess. Whether you’re working with bacterial, yeast, fungal, or mammalian cell cultures, how you supply nutrients affects everything from growth rates and yields to oxygen demand and product quality. The choice between batch, fed-batch, and continuous culture depends on your organism, application, and production goals. Fortunately, modern bioreactor systems like those from INFORS HT make it easy to implement any of these strategies at lab or pilot scale.
A bioreactor provides an ideal environment where cells can focus on what they are supposed to do: proliferate. Like lab workers, cells can only produce consistently good work if the conditions are right: it should not be too hot or too cold, and they have to have enough nutritious food and fresh air. In terms of a bioreactor, this means maintaining pH, temperature, ensuring sufficient gas supply and, depending on how the instrument has been configured, adding nutrients for successful maintenance of growth.
Monoclonal antibodies have been used for testing kits and medical therapies across a wide range of applications. The most recent is to provide a potential treatment for patients suffering from COVID-19 infection. The production of monoclonal antibodies is well understood, scalable and standardized to the extent that it makes a good generic example of a modern bioprocess. This aspect will be the focus of this short overview.
Feeding strategy is one of the most influential variables in any bioprocess. Whether you’re working with bacterial, yeast, fungal, or mammalian cell cultures, how you supply nutrients affects everything from growth rates and yields to oxygen demand and product quality. The choice between batch, fed-batch, and continuous culture depends on your organism, application, and production goals. Fortunately, modern bioreactor systems like those from INFORS HT make it easy to implement any of these strategies at lab or pilot scale.
A bioreactor provides an ideal environment where cells can focus on what they are supposed to do: proliferate. Like lab workers, cells can only produce consistently good work if the conditions are right: it should not be too hot or too cold, and they have to have enough nutritious food and fresh air. In terms of a bioreactor, this means maintaining pH, temperature, ensuring sufficient gas supply and, depending on how the instrument has been configured, adding nutrients for successful maintenance of growth.
Monoclonal antibodies have been used for testing kits and medical therapies across a wide range of applications. The most recent is to provide a potential treatment for patients suffering from COVID-19 infection. The production of monoclonal antibodies is well understood, scalable and standardized to the extent that it makes a good generic example of a modern bioprocess. This aspect will be the focus of this short overview.
Related products and services
Bioreactor services
Maintain optimal performance and longevity in your bioreactors with a range of services and support.
Bioreactor accessories
Optimize your bioreactor or fermentation systems with a comprehensive range of accessories and consumables.
Bioreactor services
Maintain optimal performance and longevity in your bioreactors with a range of services and support.
Bioreactor accessories
Optimize your bioreactor or fermentation systems with a comprehensive range of accessories and consumables.