Bioreactors and fermenters for advanced bioprocessing
Cell culture and microbial fermentation, whether involving bacteria, yeast, fungi, or mammalian cells, require tight control of process parameters, consistent scale-up, and reliable reproducibility. These needs become more complex in applications ranging from vaccine development and enzyme production to precision fermentation of alternative proteins. Learn how INFORS HT bench-top and pilot bioreactors can support your cell culture and microbial fermentation needs.
Bioreactors and fermenters for advanced bioprocessing
Cell culture and microbial fermentation, whether involving bacteria, yeast, fungi, or mammalian cells, require tight control of process parameters, consistent scale-up, and reliable reproducibility. These needs become more complex in applications ranging from vaccine development and enzyme production to precision fermentation of alternative proteins. Learn how INFORS HT bench-top and pilot bioreactors can support your cell culture and microbial fermentation needs.
Find the right bioreactor for your process
Selecting the right bioreactor or fermentor can be complex, especially when your process needs are evolving. At INFORS HT, we help scientists solve these challenges with bioreactors and fermentors designed for high-performance workflows, including batch culture, fed-batch fermentation, and perfusion. Our systems support a wide variety of applications, offering flexibility and precision from early R&D to pilot-scale and GMP-compliant production. Built on consistent design and shared control platforms, they reduce the need for revalidation and simplify the transition between volumes and applications.
Top advantages of INFORS HT bioreactors and fermentors
Inline SVG icon
Scalable design from lab to pilot
Use similar components, vessel geometries, and control systems across benchtop and pilot scales. This consistency simplifies validation, operator training, and technology transfer.
Inline SVG icon
Expert support from start to scale
From design and installation to maintenance and upgrades, our team works closely with you to adapt your system to evolving process requirements.
Inline SVG icon
Seamless data integration with eve® software
Our bioreactors connect to the eve® platform for full visibility across parameters, automated control, and reliable data tracking during batch, fed-batch, or continuous processes.
Inline SVG icon
Scalable design from lab to pilot
Use similar components, vessel geometries, and control systems across benchtop and pilot scales. This consistency simplifies validation, operator training, and technology transfer.
Inline SVG icon
Expert support from start to scale
From design and installation to maintenance and upgrades, our team works closely with you to adapt your system to evolving process requirements.
Inline SVG icon
Seamless data integration with eve® software
Our bioreactors connect to the eve® platform for full visibility across parameters, automated control, and reliable data tracking during batch, fed-batch, or continuous processes.
Benchtop bioreactors for cell culture and microbial fermentation
Early-stage research and bioprocess development often begin in small volumes. INFORS HT laboratory bioreactors are designed to provide precise control, consistent mixing, and automation-ready functionality for batch and fed-batch processes across a range of microbial and cell culture applications.
Pilot-scale bioreactors for process scale-up
Scaling up bioprocesses introduces new challenges, especially when lab-scale systems lack the control needed at production volumes. INFORS HT pilot bioreactors are built with modular components, real-time monitoring, and advanced automation to ensure what works in the lab can be reproduced at scale.
Browse all INFORS HT bioreactors
The cookbook
A guide for biotech beginners
Download this eBook for basic concepts, recipes, and strategies for bioprocesses involving cell culture and microorganisms.
Our bioreactors are trusted by scientists worldwide
The Minifors 2 was our first bioreactor, and it’s proven a reliable piece of equipment over many years. It is fully integrated with our sensors, and was great for establishing proof of concept ahead of scaling up production to larger bioreactors.
Julia ReisserCo-founder, Uluu
The seamless transition from Multifors to Labfors to Techfors-S through the unified use of eve accelerates the scale-up of our processes and helps us avoid errors.
Dr. Tobias ThieleScience Manager, Novonesis, Berlin
The Techfors-S bioreactor systems have been a key component to our mammalian cell growth in continuous culture.
Eva Bric-FurlogAutomation Specialist and Scientific Researcher at Sanofi, U.S.
The Techfors bioreactor process to be a powerful tool for our fermentation assays. Its versatile and intuitive design makes it a real pleasure to work with.
Dr. Maria Ester LuccaMicrobial Biotechnology, Proimi, Argentina
Scientific publications from our customers
See all24 Jul 2025•42 min read
Bioethanol production from organosolv treated beech wood chips obtained at pilot scale
At the University of Boras in Sweden, researchers have scaled up second-generation bioethanol production from beech wood chips using an acetone-based organosolv fractionation process. With the help of the INFORS HT Multifors bench-top bioreactor, they confirmed high fermentation efficiency at the 10-L scale, reaching ethanol yields of up to 95% from glucose-rich C6 streams. This study illustrates how optimized biomass pre-treatment and fermentation workflows can drive more efficient and scalable biofuel production.
24 Jul 2025•22 min read
The impact of annealing methods on the encapsulating structure and storage-stability of freeze-dried pellets of probiotic bacteria
At Lund University, Division of Food and Pharma, researchers studied the role of annealing in the freeze-drying of probiotic bacteria. Using the INFORS HT Multifors bioreactor and eve software, they controlled the fermentation of Limosilactobacillus reuteri to produce consistent cell cultures for downstream drying. Their results show that increased annealing time leads to thicker encapsulating structures and enhanced storage stability, providing a clearer path to developing more robust probiotic products.
15 Jul 2025•43 min read
Recycling the recyclers: strategies for the immobilisation of a PET-degrading cutinase
Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg developed and tested methods to improve the stability and recyclability of a PET-degrading enzyme for plastic recycling. Using the INFORS HT Labfors bioreactor, the team compared several immobilization strategies and found that pH-responsive polymers delivered the best results, retaining about 80% of enzyme activity and enabling up to five PET degradation cycles. In batch reactions, the process achieved more than 97% terephthalic acid yield in less than 14 hours for the first three cycles and about 78% yield in the fifth cycle. These findings support more efficient and scalable processes for enzymatic PET recycling.
24 Jul 2025•42 min read
Bioethanol production from organosolv treated beech wood chips obtained at pilot scale
At the University of Boras in Sweden, researchers have scaled up second-generation bioethanol production from beech wood chips using an acetone-based organosolv fractionation process. With the help of the INFORS HT Multifors bench-top bioreactor, they confirmed high fermentation efficiency at the 10-L scale, reaching ethanol yields of up to 95% from glucose-rich C6 streams. This study illustrates how optimized biomass pre-treatment and fermentation workflows can drive more efficient and scalable biofuel production.
24 Jul 2025•22 min read
The impact of annealing methods on the encapsulating structure and storage-stability of freeze-dried pellets of probiotic bacteria
At Lund University, Division of Food and Pharma, researchers studied the role of annealing in the freeze-drying of probiotic bacteria. Using the INFORS HT Multifors bioreactor and eve software, they controlled the fermentation of Limosilactobacillus reuteri to produce consistent cell cultures for downstream drying. Their results show that increased annealing time leads to thicker encapsulating structures and enhanced storage stability, providing a clearer path to developing more robust probiotic products.
15 Jul 2025•43 min read
Recycling the recyclers: strategies for the immobilisation of a PET-degrading cutinase
Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg developed and tested methods to improve the stability and recyclability of a PET-degrading enzyme for plastic recycling. Using the INFORS HT Labfors bioreactor, the team compared several immobilization strategies and found that pH-responsive polymers delivered the best results, retaining about 80% of enzyme activity and enabling up to five PET degradation cycles. In batch reactions, the process achieved more than 97% terephthalic acid yield in less than 14 hours for the first three cycles and about 78% yield in the fifth cycle. These findings support more efficient and scalable processes for enzymatic PET recycling.
Most popular blog
Batch, fed-batch, or continuous?
Explore how batch, fed-batch, and continuous bioprocesses differ in setup, control, and scalability. This article helps you choose the right strategy for your application and system.
Related articles
See all14 Jul 2025•10 min read•4,4•0
The difference between batch, fed-batch, and continuous processes
Feeding strategy is one of the most influential variables in any bioprocess. Whether you’re working with bacterial, yeast, fungal, or mammalian cell cultures, how you supply nutrients affects everything from growth rates and yields to oxygen demand and product quality. The choice between batch, fed-batch, and continuous culture depends on your organism, application, and production goals. Fortunately, modern bioreactor systems like those from INFORS HT make it easy to implement any of these strategies at lab or pilot scale.
14 Jul 2025•11 min read•4,4•0
What is a bioreactor and how does it work?
A bioreactor provides an ideal environment where cells can focus on what they are supposed to do: proliferate. Like lab workers, cells can only produce consistently good work if the conditions are right: it should not be too hot or too cold, and they have to have enough nutritious food and fresh air. In terms of a bioreactor, this means maintaining pH, temperature, ensuring sufficient gas supply and, depending on how the instrument has been configured, adding nutrients for successful maintenance of growth.
06 Jan 2025•6 min read•5•0
Monoclonal antibodies: From screening to production
Monoclonal antibodies have been used for testing kits and medical therapies across a wide range of applications. The most recent is to provide a potential treatment for patients suffering from COVID-19 infection. The production of monoclonal antibodies is well understood, scalable and standardized to the extent that it makes a good generic example of a modern bioprocess. This aspect will be the focus of this short overview.
14 Jul 2025•10 min read•4,4•0
The difference between batch, fed-batch, and continuous processes
Feeding strategy is one of the most influential variables in any bioprocess. Whether you’re working with bacterial, yeast, fungal, or mammalian cell cultures, how you supply nutrients affects everything from growth rates and yields to oxygen demand and product quality. The choice between batch, fed-batch, and continuous culture depends on your organism, application, and production goals. Fortunately, modern bioreactor systems like those from INFORS HT make it easy to implement any of these strategies at lab or pilot scale.
14 Jul 2025•11 min read•4,4•0
What is a bioreactor and how does it work?
A bioreactor provides an ideal environment where cells can focus on what they are supposed to do: proliferate. Like lab workers, cells can only produce consistently good work if the conditions are right: it should not be too hot or too cold, and they have to have enough nutritious food and fresh air. In terms of a bioreactor, this means maintaining pH, temperature, ensuring sufficient gas supply and, depending on how the instrument has been configured, adding nutrients for successful maintenance of growth.
06 Jan 2025•6 min read•5•0
Monoclonal antibodies: From screening to production
Monoclonal antibodies have been used for testing kits and medical therapies across a wide range of applications. The most recent is to provide a potential treatment for patients suffering from COVID-19 infection. The production of monoclonal antibodies is well understood, scalable and standardized to the extent that it makes a good generic example of a modern bioprocess. This aspect will be the focus of this short overview.
Related products and services
Bioreactor services
Maintain optimal performance and longevity in your bioreactors with a range of services and support.
Bioreactor accessories
Optimize your bioreactor or fermentation systems with a comprehensive range of accessories and consumables.
Bioreactor services
Maintain optimal performance and longevity in your bioreactors with a range of services and support.
Bioreactor accessories
Optimize your bioreactor or fermentation systems with a comprehensive range of accessories and consumables.
Consult with our experts
Reach out today to request more information regarding our bench-top and pilot scale bioreactor offering.