Rapid identification of reproductive toxicants among environmental chemicals using an in vivo evaluation of gametogenesis in budding yeast Saccharomyces cerevisiae

Researchers from the Department of Obstetrics, Gynecology, and Reproductive Sciences at the University of California, San Francisco (UCSF), have developed a high-throughput yeast assay to quickly assess the reproductive toxicity of chemicals. This innovative approach tested 179 environmental chemicals, identifying 57 with reproductive effects, and offers a promising alternative to traditional animal testing. Explore how this method could revolutionize chemical safety evaluations.