Researchers have sequenced and characterized a novel thermophilic cyanobacterium isolated from a hot spring in Namibia, revealing how it adapts to extreme heat through temperature responsive protein expression. Cultivated using the INFORS HT Labfors bench-top bioreactor, the strain proposed to represent a new genus within the Thermosynechococcaceae family displayed distinct genomic and proteomic features linked to thermotolerance. These findings expand our understanding of extremophile adaptation and highlight promising targets for future bioengineering and high temperature biotechnological applications.

In this application note, Enzyferm AS compares bioreactor and shaking flask systems for high-temperature aerobic propagation of Kveik yeast. Using the INFORS HT Minifors 2 and Multitron Standard, the study evaluates ease of use, process control, and reproducibility when working with single- and multi-strain cultures at. The results highlight how system choice impacts robustness and consistency in demanding fermentation conditions.

The Industrial Biotechnology Innovation Centre (IBioIC) in Scotland supports companies and researchers to address key challenges in biotechnology, from finding new uses for waste to developing sustainable feedstocks. By supporting researchers, startups, and SMEs, IBioIC helps move ideas out of the lab and into real-world applications that contribute to the circular bioeconomy.

Scaling microbial fermentation, when working with bacterial, fungal, or yeast-based systems, from laboratory scale to pilot or commercial production involves many challenges. Whether you are producing bacterial cultures for biopharmaceuticals, yeast for bioethanol production, fungal systems for enzyme manufacturing, or precision fermentation products, understanding these specific challenges and confidently overcoming them is important.