Life science research and development
Life science research and development
Advancing bioprocess workflows in life science research
Enhancing bioprocess workflows with superior products and services empowers researchers to focus on their core scientific mission. This commitment drives innovation and progress in biotechnology, microbiology, and pharmaceutical development, fostering advancements in life science research.
Life science research challenges
Enhancing process efficiency
Achieving optimal performance across various processes entails balancing critical parameters such as oxygen levels, pH, and agitation. Leading solutions in the market provide advanced monitoring and control features, enhancing process efficiency to ensure ideal conditions for consistent outcomes in bioprocessing endeavors.
Efficient data management
Handling and analyzing extensive experimental data present significant hurdles in life science research. Advanced software solutions offer robust tools for data management and analysis, empowering researchers to organize, visualize, and interpret data effectively. This streamlined approach is crucial for enhancing research productivity and achieving successful outcomes.
Scalability and reproducibility
Scaling experiments while maintaining reproducibility is critical in all stages of life science research. Advanced systems and software solutions facilitate seamless scale-up processes, ensuring consistency and reproducibility across different experimental scales. This capability is essential for addressing the fundamental challenge of scaling in life science research.
Enhancing process efficiency
Achieving optimal performance across various processes entails balancing critical parameters such as oxygen levels, pH, and agitation. Leading solutions in the market provide advanced monitoring and control features, enhancing process efficiency to ensure ideal conditions for consistent outcomes in bioprocessing endeavors.
Efficient data management
Handling and analyzing extensive experimental data present significant hurdles in life science research. Advanced software solutions offer robust tools for data management and analysis, empowering researchers to organize, visualize, and interpret data effectively. This streamlined approach is crucial for enhancing research productivity and achieving successful outcomes.
Scalability and reproducibility
Scaling experiments while maintaining reproducibility is critical in all stages of life science research. Advanced systems and software solutions facilitate seamless scale-up processes, ensuring consistency and reproducibility across different experimental scales. This capability is essential for addressing the fundamental challenge of scaling in life science research.
Research and development product offerings
INFORS HT is a bioprocess equipment and automation provider, offering bioreactors, incubator shakers, and bioprocess software. Our solutions support drug discovery and process development with a focus on efficiency, scalability, and reproducibility, helping to ensure optimal growth conditions and reliable research outcomes.
Incubator shakers
Discover improved efficiency and performance with INFORS HT incubator shakers. Engineered for optimal space utilization and equipped with precise temperature control, these shakers provide consistent and reproducible outcomes—setting a new standard in excellence for growth conditions.
Bioreactors
Experience groundbreaking advancements in bioprocessing with INFORS HT Bioreactors. Our cutting-edge technology introduces precision, scalability, and control to your process, optimizing productivity for life science researches. Discover how our bioreactors empower you to achieve optimal results in your bioprocess applications.
Bioprocess platform software
Explore how our software innovation is tailored for the life sciences industry. Our eve® bioprocess platform software seamlessly integrates advanced monitoring and control features into cultivation systems, offering real-time assessment of culture parameters and responsive adjustments. With online sensors and intelligent automation, life science researchers can optimize growth conditions throughout their bioprocess operations while ensuring process stability.
A guide for life science beginners
Download this eBook for basic concepts, recipes, and strategies for bioprocesses involving cell culture and microorganisms.
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See allResearchers from the University of Delaware, Departments of Chemical and Biomolecular Engineering and Electrical and Computer Engineering have made strides in enhancing the resilience of Chinese hamster ovary (CHO) cells used in biopharmaceutical production. By employing the INFORS HT Multitron incubator shaker, they exposed CHO cells to stress conditions commonly encountered during manufacturing, such as elevated levels of ammonia, lactate, and osmolality. Through comprehensive transcriptomic analysis, the team identified 199 genes exhibiting bistable expression, with seven emerging as prime candidates for engineering stress-resistant cell lines. This research holds promise for optimizing cell health and boosting productivity in large-scale bioreactor operations.
Researchers from the University of Delaware's Department of Chemical and Biomolecular Engineering have developed a site-specific integration (SSI) system to streamline CHO cell line development for monoclonal antibody (mAb) production. Using the INFORS HT Multitron incubator shaker, they cultivated cells under optimized conditions to evaluate a recombinase-mediated cassette exchange (RMCE) system that enables high-throughput transgene selection without cell sorting. Their approach resulted in a 7- to 11-fold increase in mAb productivity, offering a faster and more reliable method for biopharmaceutical manufacturing.
Researchers from Albert Einstein College of Medicine, Adimab LLC, and the U.S. Army Medical Research Institute of Infectious Diseases explored how combining neutralizing antibodies targeting different parts of the SARS-CoV-2 spike protein can help prevent escape mutants. Using the INFORS HT Multitron incubator shaker, they cultivated cells under controlled conditions to test antibody effectiveness. Their approach could strengthen antibody-based COVID-19 treatments by improving effectiveness and reducing resistance.
Researchers from the University of Delaware, Departments of Chemical and Biomolecular Engineering and Electrical and Computer Engineering have made strides in enhancing the resilience of Chinese hamster ovary (CHO) cells used in biopharmaceutical production. By employing the INFORS HT Multitron incubator shaker, they exposed CHO cells to stress conditions commonly encountered during manufacturing, such as elevated levels of ammonia, lactate, and osmolality. Through comprehensive transcriptomic analysis, the team identified 199 genes exhibiting bistable expression, with seven emerging as prime candidates for engineering stress-resistant cell lines. This research holds promise for optimizing cell health and boosting productivity in large-scale bioreactor operations.
Researchers from the University of Delaware's Department of Chemical and Biomolecular Engineering have developed a site-specific integration (SSI) system to streamline CHO cell line development for monoclonal antibody (mAb) production. Using the INFORS HT Multitron incubator shaker, they cultivated cells under optimized conditions to evaluate a recombinase-mediated cassette exchange (RMCE) system that enables high-throughput transgene selection without cell sorting. Their approach resulted in a 7- to 11-fold increase in mAb productivity, offering a faster and more reliable method for biopharmaceutical manufacturing.
Researchers from Albert Einstein College of Medicine, Adimab LLC, and the U.S. Army Medical Research Institute of Infectious Diseases explored how combining neutralizing antibodies targeting different parts of the SARS-CoV-2 spike protein can help prevent escape mutants. Using the INFORS HT Multitron incubator shaker, they cultivated cells under controlled conditions to test antibody effectiveness. Their approach could strengthen antibody-based COVID-19 treatments by improving effectiveness and reducing resistance.