Applied industries and applications

Discover how bioprocessing technologies drive innovation across diverse sectors, from advancing life science research to enhancing food production and promoting environmental sustainability. Our solutions empower breakthrough therapies, enable cutting-edge vaccine development, and fuel advancements in stem cell research. By bridging scientific ingenuity with practical applications, we're accelerating bioprocess development and optimizing production for a wide range of industries.

Applied industries and applications

Discover how bioprocessing technologies drive innovation across diverse sectors, from advancing life science research to enhancing food production and promoting environmental sustainability. Our solutions empower breakthrough therapies, enable cutting-edge vaccine development, and fuel advancements in stem cell research. By bridging scientific ingenuity with practical applications, we're accelerating bioprocess development and optimizing production for a wide range of industries.
Applied industries and applications

Applied industries

Life science research

Life science research is a dynamic field that includes biotechnology, microbiology, and pharmaceutical development. Researchers delve into cellular functions, genetic analysis, and medical treatments to drive innovation and scientific progress. Integrating cutting-edge technology and advanced laboratory instruments, this research fosters groundbreaking discoveries and advancements in health and medicine.

Food and beverage

The food and beverage industry encompasses the production, processing, and distribution of consumable goods, ranging from fresh produce to packaged snacks and beverages.

Agriculture and environmental

The agricultural and environmental sectors are pivotal for global sustainability and food security. Agriculture encompasses crop cultivation, livestock farming, and agribusiness, aiming to optimize yields while minimizing environmental harm. Concurrently, the environmental sector addresses conservation, pollution control, and sustainable resource management, crucial for ecosystem preservation and climate change mitigation. These sectors play a vital role in fostering a sustainable future, ensuring the well-being of both people and the planet.

Life science research

Life science research is a dynamic field that includes biotechnology, microbiology, and pharmaceutical development. Researchers delve into cellular functions, genetic analysis, and medical treatments to drive innovation and scientific progress. Integrating cutting-edge technology and advanced laboratory instruments, this research fosters groundbreaking discoveries and advancements in health and medicine.

Food and beverage

The food and beverage industry encompasses the production, processing, and distribution of consumable goods, ranging from fresh produce to packaged snacks and beverages.

Agriculture and environmental

The agricultural and environmental sectors are pivotal for global sustainability and food security. Agriculture encompasses crop cultivation, livestock farming, and agribusiness, aiming to optimize yields while minimizing environmental harm. Concurrently, the environmental sector addresses conservation, pollution control, and sustainable resource management, crucial for ecosystem preservation and climate change mitigation. These sectors play a vital role in fostering a sustainable future, ensuring the well-being of both people and the planet.

Applications

Monoclonal antibody production

The production of monoclonal antibodies relies heavily on cell culture techniques. Hybridoma or recombinant cell lines are cultured in controlled bioreactor systems to express and secrete specific antibodies. Optimized culture conditions and feeding strategies are essential to maximize antibody yield and maintain product quality throughout the production process.

Cell and gene therapy

Cell culture techniques are fundamental in developing and producing cell and gene therapies. These methods enable the modification, expansion, and characterization of therapeutic cells. Precise culture conditions are crucial for maintaining cell viability and function throughout the manufacturing process, ensuring the quality and efficacy of the final product.

Stem cell research

Cell culture techniques are essential in stem cell research, supporting the study of embryonic, adult, and induced pluripotent stem cells. These methods enable the isolation, expansion, and precise differentiation of stem cells into specific lineages. Carefully controlled culture environments maintain stem cell properties and guide their development, facilitating advancements in disease modeling, drug development, and regenerative medicine applications.

Cell-based vaccine production

Cell culture methods are critical in developing and manufacturing cell-based vaccines. These techniques allow for the propagation of viruses or the production of viral proteins in controlled, scalable systems. Cell culture approaches offer advantages in vaccine production speed, consistency, and adaptability compared to traditional egg-based methods.

Bacterial-based vaccines

This approach uses bioprocessing to produce vaccines using bacterial systems. Researchers engineer bacteria to produce specific antigens or immunogenic components. The process involves optimizing bacterial growth conditions, antigen expression, and purification methods. Bacterial-based vaccines offer potential advantages in production speed and scalability.

Plasmid DNA production

Microbial bioprocessing enables the production of plasmid DNA, essential for genetic engineering and some vaccine development processes. This technique involves cultivating bacteria, typically E. coli, under controlled conditions to replicate and express specific DNA sequences. The process requires careful optimization of growth conditions, nutrient supply, and extraction methods to ensure high yield and purity of the plasmid DNA. This application supports various biotechnology and pharmaceutical research efforts.

Simultaneous Saccharification and Fermentation (SSF)

SSF is a bioprocessing technique that combines the breakdown of complex carbohydrates into simple sugars (saccharification) with the fermentation of these sugars in a single step. This process, often using engineered microorganisms, can improve efficiency in biofuel production and food processing. SSF has applications in converting agricultural residues into valuable products, potentially reducing waste, and enhancing resource utilization in both food and environmental sectors.

Monoclonal antibody production

The production of monoclonal antibodies relies heavily on cell culture techniques. Hybridoma or recombinant cell lines are cultured in controlled bioreactor systems to express and secrete specific antibodies. Optimized culture conditions and feeding strategies are essential to maximize antibody yield and maintain product quality throughout the production process.

Cell and gene therapy

Cell culture techniques are fundamental in developing and producing cell and gene therapies. These methods enable the modification, expansion, and characterization of therapeutic cells. Precise culture conditions are crucial for maintaining cell viability and function throughout the manufacturing process, ensuring the quality and efficacy of the final product.

Stem cell research

Cell culture techniques are essential in stem cell research, supporting the study of embryonic, adult, and induced pluripotent stem cells. These methods enable the isolation, expansion, and precise differentiation of stem cells into specific lineages. Carefully controlled culture environments maintain stem cell properties and guide their development, facilitating advancements in disease modeling, drug development, and regenerative medicine applications.

Cell-based vaccine production

Cell culture methods are critical in developing and manufacturing cell-based vaccines. These techniques allow for the propagation of viruses or the production of viral proteins in controlled, scalable systems. Cell culture approaches offer advantages in vaccine production speed, consistency, and adaptability compared to traditional egg-based methods.

Bacterial-based vaccines

This approach uses bioprocessing to produce vaccines using bacterial systems. Researchers engineer bacteria to produce specific antigens or immunogenic components. The process involves optimizing bacterial growth conditions, antigen expression, and purification methods. Bacterial-based vaccines offer potential advantages in production speed and scalability.

Plasmid DNA production

Microbial bioprocessing enables the production of plasmid DNA, essential for genetic engineering and some vaccine development processes. This technique involves cultivating bacteria, typically E. coli, under controlled conditions to replicate and express specific DNA sequences. The process requires careful optimization of growth conditions, nutrient supply, and extraction methods to ensure high yield and purity of the plasmid DNA. This application supports various biotechnology and pharmaceutical research efforts.

Simultaneous Saccharification and Fermentation (SSF)

SSF is a bioprocessing technique that combines the breakdown of complex carbohydrates into simple sugars (saccharification) with the fermentation of these sugars in a single step. This process, often using engineered microorganisms, can improve efficiency in biofuel production and food processing. SSF has applications in converting agricultural residues into valuable products, potentially reducing waste, and enhancing resource utilization in both food and environmental sectors.

Latest articles

Blog
14 Nov. 20246 min read0
The lab partner you can count on: Multitron incubator shaker

In the fast-paced world of bioprocessing, having reliable lab equipment is critical for research and process development success. The Multitron incubator shaker has been designed with these demands in mind, offering precision and efficiency that directly address the challenges scientists face in their labs. Whether you are optimizing culture conditions or scaling up processes, the Multitron shaker provides the tools you need to advance your research with confidence.

23 Okt. 20249 min read0
Optimizing HEK293 cell cultures for gene therapy applications: the role of incubator flexibility

Gene therapy is a promising approach for treating various genetic disorders and diseases. A critical component of gene therapy is the production of viral vectors, which serve as delivery vehicles for therapeutic genes. Human Embryonic Kidney 293 (HEK293) cells have become a widely used platform for viral vector production due to their efficiency in transfection and ability to support viral replication. However, optimizing HEK293 cell cultures for large-scale production of viral vectors remains a challenge in making gene therapies more accessible and cost-effective.

16 Okt. 20248 min read0
The 7 "deadly sins" of shake flask culture

Simple actions can make a lot of difference to the outcome of your shake flasks cultures. Some beneficial ones have been covered in previous articles, however, common practices can also be a barrier to effective optimization. This article will explain why these common practices count as sins against your shake flask culture and what you can do to overcome them. 

14 Nov. 20246 min read0
The lab partner you can count on: Multitron incubator shaker

In the fast-paced world of bioprocessing, having reliable lab equipment is critical for research and process development success. The Multitron incubator shaker has been designed with these demands in mind, offering precision and efficiency that directly address the challenges scientists face in their labs. Whether you are optimizing culture conditions or scaling up processes, the Multitron shaker provides the tools you need to advance your research with confidence.

23 Okt. 20249 min read0
Optimizing HEK293 cell cultures for gene therapy applications: the role of incubator flexibility

Gene therapy is a promising approach for treating various genetic disorders and diseases. A critical component of gene therapy is the production of viral vectors, which serve as delivery vehicles for therapeutic genes. Human Embryonic Kidney 293 (HEK293) cells have become a widely used platform for viral vector production due to their efficiency in transfection and ability to support viral replication. However, optimizing HEK293 cell cultures for large-scale production of viral vectors remains a challenge in making gene therapies more accessible and cost-effective.

16 Okt. 20248 min read0
The 7 "deadly sins" of shake flask culture

Simple actions can make a lot of difference to the outcome of your shake flasks cultures. Some beneficial ones have been covered in previous articles, however, common practices can also be a barrier to effective optimization. This article will explain why these common practices count as sins against your shake flask culture and what you can do to overcome them. 

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