Data sheetPDF
Bench-top Bioreactor | 100 mL-10 L | Cell Culture and Microbial
Multifors 3
Bench-top Bioreactor | 100 mL-10 L | Cell Culture and Microbial
Multifors 3
A bioreactor designed for reproducible process development and technology transfer
The Multifors 3 bench-top bioreactor carries the complete control strategy into every run, not just setpoints, helping laboratories generate reproducible results and simplify technology transfer. Together with eve® bioprocess software, the strategy is defined in advance, understood and executed by Multifors 3, and documented end-to-end to improve consistency from one run to the next.Why should you choose Multifors 3?
Save time with reproducible process control
Reproducibility depends on more than setpoints. Multifors 3 plans, executes, and captures the complete control strategy, including controller presets, PID settings, cascades, and hardware configuration, and sensor metadata. When transferring a process, or switching between workflows, the complete process definition travels with it, reducing variability and making reproducibility more predictable.
Be confident with reliable process execution
Critical experiments shouldn't depend on network availability or software updates. Multifors 3 is designed to keep processes running without interruption while supporting FAT/SAT qualification and deployment in GMP environments, giving laboratories confidence throughout process development and beyond.
Future proof with an open, scalable platform
As process requirements evolve, your bioreactor platform should evolve with them. Multifors 3 supports glass vessels from 100 mL to 10 L and single-use vessels from multiple suppliers, with up to six bioreactors operated from a single touchscreen. Built on open communication standards, it gives laboratories the flexibility to integrate new peripherals, digital sensors, and software while maintaining a single platform across changing applications and workflows.
Save time with reproducible process control
Reproducibility depends on more than setpoints. Multifors 3 plans, executes, and captures the complete control strategy, including controller presets, PID settings, cascades, and hardware configuration, and sensor metadata. When transferring a process, or switching between workflows, the complete process definition travels with it, reducing variability and making reproducibility more predictable.
Be confident with reliable process execution
Critical experiments shouldn't depend on network availability or software updates. Multifors 3 is designed to keep processes running without interruption while supporting FAT/SAT qualification and deployment in GMP environments, giving laboratories confidence throughout process development and beyond.
Future proof with an open, scalable platform
As process requirements evolve, your bioreactor platform should evolve with them. Multifors 3 supports glass vessels from 100 mL to 10 L and single-use vessels from multiple suppliers, with up to six bioreactors operated from a single touchscreen. Built on open communication standards, it gives laboratories the flexibility to integrate new peripherals, digital sensors, and software while maintaining a single platform across changing applications and workflows.
Designed for modern bioprocess development workflows
- Process development: Build, compare, and refine bioprocess strategies with complete control over every run to generate reproducible results with confidence.
- Parallel bioprocessing: Run up to six vessels from one touchscreen while automatically applying controller presets across every bioreactor, reducing setup time, minimizing manual errors, and supporting reproducible technology transfer.
- Flexible bioprocess workflows: Support cell culture, perfusion, cell and gene therapy, and microbial fermentation with glass and single-use vessel options on one flexible platform.
eve® bioprocess software: The intelligence inside Multifors 3
The Multifors 3 bench-top bioreactor and eve® bioprocess software work together to plan, execute, and capture the complete control strategy from every process, not just the setpoints. From recipe creation and controller presets to hardware configuration, process parameters, and documentation, every process parameter is planned and captured end-to-end to improve reproducibility, simplify technology transfer, and reduce the time and risk associated with manually configuring new experiments.
Product specifications
| Vessel sizes (and working volumes) | 375 mL (0.1-0.25 L), 750 mL (0.2-0.5 L), 1.5 L (0.33-1 L), 3.75 L (0.83-2.5 L), 7.5 L (1.75-5 L), and 15 L (3.3-10 L) glass vessels with compatibility for single-use vessels from multiple established suppliers. |
| Integrated control | Up to 8 integrated pumps per vessel, integrated gas mixing, perfusion control, balance connectivity, and unparalleled sensor density to support advanced process monitoring. |
| Sensor compatibility | Broad compatibility with leading analog and digital sensors for a wide range of parameters, supporting flexible integration with a wide range of process analytical technologies. |
| Connectivity | Open communication through OPC UA, REST APIs, eve® bioprocess software, and support for FAT/SAT qualification. |
| Parallel operation | Up to 2 bioreactors individually controlled per control tower and up to 6 bioreactors operated from a single touchscreen. Plan, manage and monitor up to 99 parallel batches across multiple Multifors 3 systems with eve® bioprocess software. |
Application Note
CHO cell perfusion cultivation with the Multifors 3 bench-top bioreactor
Explore a 23-day NIST CHO perfusion cultivation on the Multifors 3 bench-top bioreactor with the Multifors 3 Perfusion Package. The culture was held at 23–30 × 10⁶ cells/mL and 2 vvd with viability above 95%, using gravimetric volume and feed control from balances connected directly to the controller and automated bleed control on inline capacitance. Volume, feed rate, pH, dissolved oxygen and biomass were all configured in eve® and executed on the Multifors 3.
Product downloads
Application notePDF
BrochurePDF
BrochurePDF
What our customers say about Multifors 3
After testing the Multifors 3 with our highly demanding Pichia pastoris fermentations, we are very pleased with its performance. Our processes require high oxygen transfer rates and efficient heat removal, and the system has allowed us to achieve very high cell densities consistently. The twin architecture helps us obtain results faster and accelerate process development. We also highly appreciate the versatility of the eve® software, which allows us to program very complex fermentation strategies and implement real-time soft sensors for improved process monitoring and understanding. Overall, it has been a very powerful and flexible platform for our work.
Xavier Garcia OrtegaBioprocess Engineering Associate Professor, Universitat Autònoma de Barcelona
After having thoroughly evaluated the Multifors 3 for our demanding continuous perfusion cultivations, we are very pleased with its performance. Continuous bioprocessing is generally characterized by substantial operational complexity, yet the system’s architecture effectively minimized the hardware and IT integration challenges which could be typically encountered. Thus, it allowed us to achieve stable steady-state conditions at high viable cell density in long-term runs. Moreover, combined with the versatility of the eve® control software, the Multifors 3 proved to be a reliable, flexible and robust platform for advancing and developing continuous mammalian biomanufacturing processes.
Giovanni CeresaScientific Assistant, FHNW Institute for Pharmatech and Biotech
As an upstream viral vector team leader, I have worked with several manufacturer's bioreactor systems through the development chain and into full-scale manufacturing. The INFORS HT Multifors 3 bench-top bioreactor with a dual controller paired with their 250 mL and 500 mL bioreactor vessels has proven to be an effective bioreactor for production of both AAV and LVV. The well thought-out headplate design allows for multiple run designs, and the simple, yet powerful software enables training through advanced control of the process.
Matt Ercolino Senior Biolab Manager, Kyfora Bio by Polysciences
Request a quote
Reach out today to request a quote or more information regarding our Multifors 3 bench-top bioreactor.
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